The most prominent candidates to win the Serie A Calcio title

Football fans are gearing up for the start of the new 2025-26 Serie A season, scheduled for Saturday, August 23. The opening day will witness two exciting matches between Genoa and Lecce, while defending champions Napoli will face Sassuolo at the start of their title defense. According to Opta's predictions, Inter Milan is the favorite to win the title this season with a 35.9% chance, despite losing the title last season by one point to Napoli. The network added that Inter had the strongest attack last season, scoring 79 goals, and had the second-best defense in the league after Napoli, making them a major contender for the top spot under their new coach Cristian Chivu, who succeeded Simone Inzaghi. Defending champions Napoli, under coach Antonio Conte, have a 13.7% chance of retaining the title despite strengthening their squad with strong signings, most notably Belgian veteran Kevin De Bruyne, in addition to young striker Lorenzo Lucca and winger Noah Lang. Conte hopes to draw on his extensive experience in Serie A, boasting the highest points average in the history of the competition, averaging 2.24 points per game since the introduction of the three-point system. Meanwhile, Atalanta continues its quest to remain competitive despite the departure of its legendary coach, Gian Piero Gasperini, after nine successful seasons during which he led the team in 342 matches. Despite losing their top scorer, Matteo Retegui, to Saudi club Al-Qadisiyah after scoring 25 goals last season, the team's odds are on at least a 12.8% chance of winning the title, pending a decision on the future of Nigerian Ademola Lookman, who contributed to 57 goals in three seasons. Roma, under new coach Gasperini, are fourth among the favorites with a 9.9% chance, followed by Juventus with an 8.2% chance, with both teams expected to be content with competing for at least the Champions League spots this season.